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Postdoc in Cell Biology/Cancer metastasis 927849

Postdoc in Cell Biology/Cancer metastasis

A Post Doctoral position of two years is vacant as of 1 December 2017 at Department of Engineering (ENG) at Aarhus University, Denmark.

Metastasis is the major cause of death in cancer patients accouting for about 90% of the mortality. Their detection and analysis of the hallmark of metastasis, circulating tumor cells (CTCs), have significant impacts in cancer biology and clinical practice. However, CTCs are extremely rare events and contain heterogeneous subpopulations, which hampers their medical applications. Here we aim to build 3D nano-biointerfaces specifically designed for capturing, enumeration and 3D culture of CTCs. Key to this 3D nanobiointerface is the use of innovative electrospinning technology for cost-effective fabrication of 3D biofunctional microfibrous matrix with nano-featured ultra-high surface areas for A) CTCs capture and analysis, and B) home CTCs to propagate and build a in vitro 3D metastasis model for testing drug sensitivity. A successful outcome will assist the realization of point-of-care diagnosis and individualized treatment of cancers by non-invasive and convenient tests in the future.

The project is funded by Independent Research Fund Denmark and aimed at developing novel electrospun biomimetic nanofibres for the next generation of biomedical cancer research devices.

The successful candidate will be involved in intensive interdisciplinary collaborations with local partners at Aarhus University Hospital and international partners in US (Harvard Univ., Brandeis Univ.) and Israel (Technion) to work on material development, surface cancer biomarker bioconjugation, CTC enumeration and in vitro cancer biology studies.

Educational qualifications
The applicant should have a completed PhD in cell biology, cancer metastasis or relevant.

We are seeking candidates with a background in cell biology, cancer biomarkers, tissue engineering or related disciplines. Favored practical skills involve cancer biomarker, surface bioconjugation, immunohistochemistry, qPCR, flow cytometry, confocal microscopy and electron microscopy. A strong background in CTC enrichment and 3D cell culture is desired.

The Engineering Department, www.eng.au.dk, within the faculty of science and technology (ST) Denmark promotes and develops Engineering research and education at Aarhus University. The Department undertakes engineering research and education within classical engineering disciplines (Mechanical, IT, civil and architectural, Chemical and biotechnology) in close collaboration with other departments at ST and the School of Engineering at ST. Department of Engineering offers a dynamic, interdisciplinary research environment with many national and international collaborators in science and industry.

Place of Employment and Place of Work
The place of employment is Aarhus University, and the place of work is Science and Technology, Gustav Wieds Vej 10, DK-8000 Aarhus C, Denmark.

For more information about the position contact assistant professor Menglin Chen, e-mail: menglin@eng.au.dk


Application procedure
Short-listing is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants, including the main considerations emphasized during the selection process.

Formalities and salary range
Science and Technology refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.
The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.
Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Finance and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities. Salary depends on seniority as agreed between the Danish Ministry of Finance and the Confederation of Professional Associations.
All interested candidates are encouraged to apply, regardless of their personal background.
Aarhus University offers Relocation service to International researchers. You can read more about it here.

Ansøgningsfrist

Alle ansøgninger skal være lavet online og modtaget senest:

01.11.2017
Søg stilling online her

 

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